Sitagliptin: What You Should Know

Last Updated on Thu, 18 May 2023 | Drug References

Sitagliptin, a medication prescribed by a doctor to treat diabetes type 2, is available on prescription. Januvia is another name for the drug. This drug belongs to the DPP-4 class which helps lower blood sugar in type 2 diabetics. The drug increases the level of hormones which help to increase Insulin production and absorption from bloodstream.

The most common form of diabetes, type 2, is caused by high blood sugar levels. Type 2 diabetics may suffer from symptoms like excessive thirst, frequent urine, fatigue, loss of weight, blurred sight, and slow wound healing. Untreated type 2 diabetes may lead to complications such as kidney disease, heart disease and stroke.

Sitagliptin: What is its Use?

Sitagliptin improves glycemic (blood sugar) control in type 2 diabetic adults. The drug reduces the amount sugar in blood by releasing more insulin and decreasing sugar production in the liver. To maximize the drug's effects, It Is often prescribed with Metformin and other medications for diabetes.

Clinical studies have shown that sitagliptin reduces A1C levels (measure of blood glucose averages over two to three months) on average by 0. 9% -1. 7% . However, there are other benefits such as improved cholesterol and a reduced risk of hypoglycemia.

Sitagliptin: Benefits and Side Effects

According to research , sitagliptin may help those with type 2 diabetics achieve better control of their blood sugar levels. It may also reduce cardiovascular risks, including heart attacks and strokes, as well as improve cholesterol levels. Sitagliptin has also been found to provide protection from kidney disease for people with type-2 diabetes.

Sitagliptin can also help people manage blood sugar with lifestyle and diet changes. It may reduce the use of other diabetes medication and reduce long-term complications related to type 2 diabetes.

Sitagliptin Side Effects

Sitagliptin, like all medicines, can have side effects. Most common are nausea, headaches, upper respiratory infections, and diarrhea. Other less common side effects include joint pain and skin rash. They also can cause swelling in the mouth, face, lips and throat. Rarely, sitagliptin can cause an allergic response that is life-threatening. Seek medical help immediately if you notice any symptoms of an allergy reaction.

Sitagliptin may also interact with other medications such as beta-blockers and diuretics. Inform your doctor of all medications that you take before beginning sitagliptin. You doctor will adjust the dose to prevent any potential interactions.

Sitagliptin: Experts and professionals' opinions

Sitagliptin is generally considered an effective option to treat type 2 diabetes by experts. It is well tolerated and helps improve glycemic management and lower the risk of complications. They caution, however, that the supplement should not replace lifestyle changes such as diet or exercise which are vital for overall health.

Experts also recommend closely monitoring your blood sugar level while you are taking sitagliptin. It is recommended that you discuss any side effects with your doctor and seek medical treatment if the symptoms become serious.

Sitagliptin: How to Start?

Sitagliptin can be taken once daily with or without meals. Starting dose of 25mg, once daily is recommended. If necessary, your doctor can increase the dose up to 50mg once daily. Take no more than 50mg per day.

Follow your doctor's directions when taking sitagliptin. Consult your doctor before you skip doses, or discontinue taking this medication. Monitor your blood glucose levels while you are taking sitagliptin.

Sitagliptin comes in tablet form and is taken one time daily. The generic version is also available under the name Januvia. Most pharmacies as well as online retailers carry it.

What are the side effects to be aware of?

Sitagliptin, when used as prescribed, is safe in general. Like all medicines, sitagliptin can have side effects. Most common side effects include headaches, nausea, diarrhea and upper respiratory infections. Other less common side effects include joint pain and skin rash. They also can cause swelling in the mouth, face, lips and throat. Rarely, sitagliptin can cause an allergic response that is life-threatening. Seek medical help immediately if you notice any symptoms of an allergy reaction.

Conclusion

Sitagliptin, a medication prescribed by a doctor to treat diabetes type 2, is available on prescription. Sitagliptin belongs to the class of DPP-4 Inhibitors that help reduce blood sugar in those with type 2 diabetics. Clinical studies have shown that sitagliptin improves glycemic management, lowers the risk of cardiovascular disease, and increases cholesterol. The drug is taken daily with or without eating, in either generic or brand form.

Sitagliptin, like all medicines, can have side effects, such as headaches, nausea, diarrhea and skin rash. Rarely, sitagliptin can cause an allergic response that is life-threatening. Sitagliptin can interact with other medications. Tell your doctor if you take any before taking it. Sitagliptin is an effective option to treat type 2 diabetics, but should not replace lifestyle changes such as exercise and diet.