What Is Darunavir? What Are Its Applications?

Darunavir, an antiviral medication used for HIV infection treatment. Janssen Pharmaceuticals markets it under the name Prezista. The drug belongs to the protease-inhibitor class, and works by blocking HIV-1 protease enzyme, which the virus needs to reproduce in the body. Darunavir can be prescribed with other HIV drugs to reduce viral loads and achieve undetectable viral loads.

Darunavir: Uses and Benefits

The U.S. Food and Drug Administration has approved Darunavir to treat HIV in children and adults aged three years and over. Darunavir has been shown to reduce HIV viral loads and increase CD4+ cells in clinical trials . Darunavir is also effective at treating HIV-1 that has become resistant to protease-inhibitor-based regimens. Darunavir usually comes in combination with HIV medication. Common combinations include ritonavir ( Norvir ), cobicistat (Tybost), emtricitabine/tenofovir disoproxil fumarate (Truvada), and abacavir/ Lamivudine (Epzicom). Darunavir plus 100mg ritonavir twice a day is a common adult regimen. Children aged between 12 and 17 years are recommended to take darunavir 800 mg with ritonavir taken twice daily.

Darunavir: Benefits and Side Effects

Darunavir is effective at reducing HIV virus load and increasing CD4+ cells. Darunavir users had significantly more success in achieving undetectable viral loads than those who did not take the drug. Darunavir is also effective at treating HIV-1 that has become resistant to protease-inhibitor-based regimens. Darunavir is well tolerated, and there are few reported side effects.

Darunavir Side Effects

Darunavir can cause nausea, vomiting diarrhea headache and rashes. Rarer but more serious side effects include kidney and liver issues, as well as changes in blood glucose levels. If any of these symptoms occur, patients should contact their doctor. Darunavir may also interact with other medications or supplements. Patients should tell their doctors if they take any of these.

Darunavir: Expert opinions

Darunavir, according to experts, is an effective and safe treatment for HIV. It has been shown to be effective at reducing viral loads and increasing CD4+ counts. The drug is well tolerated and causes few side effects. Darunavir also works well in HIV-1 patients who are resistant to protease-inhibitor-based regimens. Darunavir should be taken in conjunction with other HIV drugs for best results, according to experts.

Darunavir: How to Start?

Darunavir comes in both tablet and suspension oral form. Adults should take 800mg twice daily orally with food. Children aged 3-11 years should take 400mg orally, twice daily. Children aged 12-17 years should take 600mg twice daily orally with food. Darunavir is best taken with HIV medication. When taking darunavir, It Is essential to adhere to your doctor's directions. Darunavir can have side effects. Nausea, vomiting, diarrhea and headache are all common side effects. Contact your doctor if you notice any side effects. Darunavir can cause interactions with other medications or supplements. Tell your doctor if you take any of these.

Conclusion

Darunavir, an antiviral medication used for HIV treatment. Darunavir is an antiviral drug that reduces HIV viral loads and increases CD4+ cells counts. It is also well tolerated and comes with few side effects. To maximize the effectiveness of darunavir, it should be used in conjunction with other HIV medication. Darunavir can have side effects or drug interactions. If you are concerned about darunavir, speak to your doctor.

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